NowarskiLAB


Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity.
Jarret, A., R. Jackson, C. Duizer, M. E. Healy, J. Zhao, J. M. Rone, P. Bielecki, E. Sefik, M. Roulis, T. Rice, K. N. Sivanathan, T. Zhou, A. G. Solis, H. Honcharova-Biletska, K. Velez, S. Hartner, J. S. Low, R. Qu, M. R. de Zoete, N. W. Palm, A. M. Ring, A. Weber, A. E. Moor, Y. Kluger, R. Nowarski*, and R. A. Flavell*. 2020
Cell 180: 50-63 e12.

Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense.
Lai, N. Y., M. A. Musser, F. A. Pinho-Ribeiro, P. Baral, A. Jacobson, P. Ma, D. E. Potts, Z. Chen, D. Paik, S. Soualhi, Y. Yan, A. Misra, K. Goldstein, V. N. Lagomarsino, A. Nordstrom, K. N. Sivanathan, A. Wallrapp, V. K. Kuchroo, R. Nowarski, M. N. Starnbach, H. Shi, N. K. Surana, D. An, C. Wu, J. R. Huh, M. Rao, and I. M. Chiu. 2020
Cell 180: 33-49 e22.

The Stromal Intervention: Regulation of Immunity and Inflammation at the Epithelial-Mesenchymal Barrier.
Nowarski, R., R. Jackson, and R. A. Flavell. 2017
Cell 168: 362-375.

Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis.
Nowarski, R., R. Jackson, N. Gagliani, M. R. de Zoete, N. W. Palm, W. Bailis, J. S. Low, C. C. Harman, M. Graham, E. Elinav, and R. A. Flavell. 2015.
Cell 163: 1444-1456.

NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion.
Wlodarska, M., C. A. Thaiss, R. Nowarski, J. Henao-Mejia, J. P. Zhang, E. M. Brown, G. Frankel, M. Levy, M. N. Katz, W. M. Philbrick, E. Elinav, B. B. Finlay, and R. A. Flavell. 2014.
Cell 156: 1045-1059.


Innate immune cells in inflammation and cancer.
Nowarski, R., N. Gagliani, S. Huber, and R. A. Flavell. 2013.
Cancer Immunology Research 1: 77-84.
Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms.
Elinav, E., R. Nowarski, C. A. Thaiss, B. Hu, C. Jin, and R. A. Flavell. 2013.
Nature Reviews Cancer 13: 759-771.


APOBEC3 cytidine deaminases in double-strand DNA break repair and cancer promotion.
Nowarski, R., and M. Kotler. 2013.
Cancer Research 73: 3494-3498.
APOBEC3G enhances lymphoma cell radioresistance by promoting cytidine deaminase-dependent DNA repair.
Nowarski, R., O. I. Wilner, O. Cheshin, O. D. Shahar, E. Kenig, L. Baraz, E. Britan-Rosich, A. Nagler, R. S. Harris, M. Goldberg, I. Willner, and M. Kotler. 2012.
Blood 120: 366-375.

Hypermutation by intersegmental transfer of APOBEC3G cytidine deaminase.
Nowarski, R., E. Britan-Rosich, T. Shiloach, and M. Kotler. 2008.
Nature Structural & Molecular Biology 15: 1059-1066.