NowarskiLAB
A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance
Randall T Mertens, Aditya Misra, Peng Xiao, Seungbyn Baek, Joseph M Rone, Davide Mangani, Kisha N Sivanathan, Adedamola S Arojojoye, Samuel G Awuah, Insuk Lee, Guo-Ping Shi, Boryana Petrova, Jeannette R Brook, Ana C Anderson, Richard A Flavell, Naama Kanarek, Martin Hemberg, Roni Nowarski. 2024
Immunity 57:2077-2094
Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling
Paolo Cadinu, Kisha N. Sivanathan, Aditya Misra, Rosalind J. Xu, Davide Mangani, Evan Yang, Joseph M. Rone, Katherine Tooley, Yoon-Chul Kye, Lloyd Bod, Ludwig Geistlinger, Tyrone Lee, Noriaki Ono, Gang Wang, Liliana Sanmarco, Francisco J. Quintana, Ana C. Anderson, Vijay K. Kuchroo, Jeffrey R. Moffitt*, Roni Nowarski*. 2024
Cell 187:2010-2028
Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity
Jarret, A., R. Jackson, C. Duizer, M. E. Healy, J. Zhao, J. M. Rone, P. Bielecki, E. Sefik, M. Roulis, T. Rice, K. N. Sivanathan, T. Zhou, A. G. Solis, H. Honcharova-Biletska, K. Velez, S. Hartner, J. S. Low, R. Qu, M. R. de Zoete, N. W. Palm, A. M. Ring, A. Weber, A. E. Moor, Y. Kluger, R. Nowarski*, and R. A. Flavell*. 2020
Cell 180: 33-49 e22.
Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense
Lai, N. Y., M. A. Musser, F. A. Pinho-Ribeiro, P. Baral, A. Jacobson, P. Ma, D. E. Potts, Z. Chen, D. Paik, S. Soualhi, Y. Yan, A. Misra, K. Goldstein, V. N. Lagomarsino, A. Nordstrom, K. N. Sivanathan, A. Wallrapp, V. K. Kuchroo, R. Nowarski, M. N. Starnbach, H. Shi, N. K. Surana, D. An, C. Wu, J. R. Huh, M. Rao, and I. M. Chiu. 2020
Cell 180: 33-49 e22.
NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion
Wlodarska, M., C. A. Thaiss, R. Nowarski, J. Henao-Mejia, J. P. Zhang, E. M. Brown, G. Frankel, M. Levy, M. N. Katz, W. M. Philbrick, E. Elinav, B. B. Finlay, and R. A. Flavell. 2014
Cell 156: 1045-1059.
