We study the crosstalk between tissue and immune cells and the principles governing tissue regulation of immunity and inflammation
Tissue Regulation of Immunity and Inflammation
Our laboratory studies how tissues orchestrate the immune response in the setting of inflammation. The questions we pursue are grounded in understanding the interplay between tissue physiology and the innate immune system, as a central axis controlling homeostasis and disease. Using advanced genetic models and imaging platforms, we strive to identify the complex immunological crosstalk and immunoregulatory pathways controlling protective and pathological inflammation.
Our Research Team
With affiliations at the Evergrande Center for Immunologic Diseases, Harvard Medical School, Brigham & Women's Hospital and the Broad Institute, our group combines immunology, cell biology and computational modeling to dissect complex mechanisms of immune regulation within tissues.